How to get and use Malignant Hearts in Diablo 4 season 2

Summon a new end game boss with this item.

Woman with shaved head wearing skeletal armor in Diablo 4
Image via Blizzard Entertainment

Malignant Hearts have been relegated to a simple purpose in Diablo 4 and that is summoning the Echo of Varshan, an end-game boss.

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If you are trying to find Malignant Hearts, and the other components necessary to summon Varshan, here’s what you need to do.

Where to get Malignant Hearts in Diablo 4 season two

A player in Diablo 4 stood in front of the Tree of Whispers.
An effective way of earning great gear. Screenshot by Dot Esports

You can obtain Malignant Hearts, as well as the other Malignant Body Parts necessary to summon the Echo of Varshan, by completing Whispers of the Dead quests. You can start these quests by venturing to the Tree of Whispers in the northeastern parts of Hawezar. Before you begin questing, you should know that Malignant Hearts only drop from quests at World Tier Four.

Aside from the Tree of Whispers, you can also get random Malignant Body Parts by killing Grotesque Debtors. You can typically find these enemies in Legion events or in areas that have Grim Favor rewards.

Though you can grind killing Grotesque Debtors much more frequently, I found that completing the Tree of Whisper activities was the much easier way to acquire Malignant Hearts and the other needed Malignant Body Parts.

Best way to farm Malignant Hearts in Diablo 4 Season 2

The most efficient way you can get your hands on Malignant Hearts in Diablo 4 is to defeat elite enemies when they spawn after world bosses and events.

Tip:

Malignant Hearts will only spawn in World Tier 4 in Diablo 4.

Defeating the World Boss Tier 4 and collecting Whispers is another great way to farm Malignant Hearts in Diablo 4. The World Boss will drop Malignant Hearts.

How to use Malignant Hearts in Diablo 4 season two

Here are all four Malignant Body Parts you will need to summon Echo of Varshan:

  • Malignant Heart
  • Gurgling Head
  • Trembling Hand
  • Blackened Femur

To do this, you need to venture to The Writhing Mire area just beside the Tree of Whispers in the northeastern Hawezar region.

Varshan is not a difficult boss to beat on your own, though there are a few mechanics you should know beforehand. I found it important to avoid staying in front of Varshan to avoid his Explosive Decay attack. I also brought plenty of Poison Resistant potions to stave off his DoT attacks—and believe me, I needed them.

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Blaine Polhamus
Staff Writer for Dot Esports. Avid gamer for two decades and gaming writer for three years. I'm a lover of anything Souls-like since 2011. I cover everything from single-player RPGs to MMOs.
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Dominique' McClain
Dominique' McClain is a passionate writer on anything Esports and video games. She has 4+ years of experience covering games in the industry and enjoys Overwatch 2, Fortnite, and Elden Ring.